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Vasorelaxing action of vasonatrin peptide is associated with activation of large-conductance Ca2+-activated potassium channels in vascular smooth muscle cells
The aim of this study was to test the hypothesis that vasorelaxing action of vasonatrin peptide (VNP) is due to activation of the large-conductance Ca2+-activated potassium channel (BKCa) via guanylyl cyclase (GC)-coupled natriuretic peptide receptors (NPRs) in vascular smooth muscle cells (VSMCs). Contraction experiments were performed using human radial artery, whereas BKCa current by patch clam…
Creator
- Yu, J.
- Zhu, M.
- Fu, Z.
- Zhu, X.
- Zhao, Y.
- Chen, B.
Subject
- Fyziologie člověka a srovnávací fyziologie
- natriuretické peptidy
- natriuretic peptides
- vasonatrin peptide
- vascular smooth muscle cells
- calcium-activated potassium channels
- cyclic guanosine monophosphate
- 14
- 612
Type of item
- article
- články
- model:article
Creator
- Yu, J.
- Zhu, M.
- Fu, Z.
- Zhu, X.
- Zhao, Y.
- Chen, B.
Subject
- Fyziologie člověka a srovnávací fyziologie
- natriuretické peptidy
- natriuretic peptides
- vasonatrin peptide
- vascular smooth muscle cells
- calcium-activated potassium channels
- cyclic guanosine monophosphate
- 14
- 612
Type of item
- article
- články
- model:article
Providing institution
Aggregator
Rights statement for the media in this item (unless otherwise specified)
- http://creativecommons.org/licenses/by-nc-sa/4.0/
Rights
- policy:public
Source
- Physiological research | 2010 Volume:59 | Number:2
Identifier
- uuid:bcd7c40c-4fc6-4f3e-b3f3-57d7b0c1def5
- https://cdk.lib.cas.cz/client/handle/uuid:bcd7c40c-4fc6-4f3e-b3f3-57d7b0c1def5
- uuid:bcd7c40c-4fc6-4f3e-b3f3-57d7b0c1def5
Format
Language
- eng
- eng
Providing country
- Czech Republic
Collection name
First time published on Europeana
- 2021-06-01T12:19:28.026Z
Last time updated from providing institution
- 2021-06-01T12:19:28.026Z